| 货号 | 0298/50 |
| 别名 | L-trans-Pyrrolidine-2,4-dicarboxyli |
| 供应商 | Tocris |
| 生物活性 | Potent, competitive, transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor. Also available as part of the Excitatory Amino Acid Transporter Inhibitor Tocriset™. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >97 % |
| 计算分子量 | 159.14 |
| 分子式 | C6H9NO4 |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 64769-66-0 |
| 参考文献 | Zuiderwijket al (1996) Effects of uptake carrier blockers SK & F 89976-A and L-trans-PDC on in vivo release of amino acids in rat hippocampus. Eur.J.Pharmacol. 307 275. PMID: 8836615. Mitrovic and Johnston (1994) Regional differences in the inhibition of L-glutamate amd L-aspartate sodium-dependent high affinity uptake systems in rat CNS synaptosomes by L-trans-pyrrolidine-2,4-dicarboxylicthreo-3-hydroxy-D-aspartate and D-aspartate. Neurochem.Int. 24 583. PMID: 7981641. Bridgeset al (1991) Conformationally defined neurotransmitter analogues. Selective inhibition of glutamate uptake by one pyrrolidine-2,4-dicarboxylate diastereomer. J.Med.Chem. 34 717. PMID: 1671706. |