| 货号 | 2397/50 |
| 别名 | (7α,11α,17α)-9,11-Epoxy-17-hydroxy-3-o |
| 供应商 | Tocris |
| 生物活性 | Selective mineralocorticoid (aldosterone) receptor antagonist (IC50 = 360 nM). Displays > 27-fold selectivity over androgen, progesterone and estrogen receptors (IC50 > 10 μM). Orally active antihypertensive in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 414.5 |
| 分子式 | C24H30O6 |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO |
| CAS号 | 107724-20-9 |
| 参考文献 | McMahon and Cunningham (2001) Recent studies with eplerenone, a novel selective aldosterone receptor antagonist. Curr.Opin.Pharmacol. 1 190. PMID: 11714095. De Gasparoet al (1987) Three new epoxy-spirolactone derivatives: characterization in vivo and in vitro. J.Pharmacol.Exp.Ther. 240 650. PMID: 2949071. |