C 87 (50 MG)
货号：
5484/50 基本售价：
9597.2 元 规格：
50 mg
产品信息
概述| 货号 | 5484/50 |
| 别名 | 3-Phenyl-1-(4-phenyl-2-thiazolyl)-1H-pyrazole-4,5-dione 4-[2-(4-chloro-3-nitrophenyl)hydrazone] |
性能| 供应商 | Tocris |
| 生物活性 | TNF-α inhibitor (Kd = 110 nM for hTNF-α). Inhibits TNF-α-induced cytotoxicity in L929 fibroblast cells. Attenuates inflammation and increases survival in a mouse hepatitis model. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 502.93 |
| 分子式 | C24H15ClN6O3 |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO |
| 参考文献 | Maet al (2014) A novel small-molecule tumor necrosis factor α inhibitor attenuates inflammation in a hepatitis mouse model. J.Biol.Chem. 289 12457. PMID: 24634219. |
