| 货号 | 1133/50 |
| 别名 | 2-[(4,5-Dihydro-1H-imidazol-2-yl)me |
| 供应商 | Tocris |
| 生物活性 | Selectiveα2A-adrenoceptor antagonist (Ki = 1.7 nM and 144.5 nM at α2Aandα2B-adrenergic receptors respectively). Increases hippocampal noradrenalin release following systemic administration. Also available as part of the α2-Adrenoceptor Tocriset™. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 331.37 |
| 分子式 | C13H17N3.C4H4O4 |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 118343-19-4 |
| 参考文献 | Calladoet al (1999) α2A-But not α2B/C-adrenoceptors modulate noradrenaline release in rat locus coeruleus: voltammetric data. Eur.J.Pharmacol. 366 35. PMID: 10064149. Gavinet al (1997) α2C-adrenoceptors mediate contractile responses to noradrenaline in the human saphenous vein. Naunyn Schmiedebergs Arch.Pharmacol. 355 406. PMID: 9089673. Kisset al (1995) Subtype-specificity of the presynaptic α2-adrenoceptors modulating hippocampal norepinephrine release in rat. Brain Res. 674 238. PMID: 7796102. Younget al (1989) Novel α2-adrenoceptor antagonists show selectivity for α2A- and α2B-adrenoceptor subtypes. Eur.J.Pharmacol. 168 381. PMID: 2573535. |