| 货号 | 1105/50 |
| 别名 | 11-[[2-[(Diethylamino)methyl]-1-pip |
| 供应商 | Tocris |
| 生物活性 | Selective M2 muscarinic receptor antagonist. Ki values are 64, 417, 786, 211 and 5130 nM for human recombinant M2, M1, M3, M4 and M5 muscarinic receptors, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 421.54 |
| 分子式 | C24H31N5O2 |
| 可溶性/溶解性 | Soluble to 25 mM in DMSO with gentle warming |
| CAS号 | 102394-31-0 |
| 参考文献 | Mansfieldet al (2005) Muscarinic receptor subtypes in human bladder detrusor and mucosa, studied by radioligand binding and quantitative competitive RT-PCR: changes in ageing. Br.J.Pharmacol. 114 1089. PMID: 15723094. Eglenet al (1996) Muscarinic receptor subtypes and smooth muscle function. Pharmacol.Rev. 48 531. PMID: 8981565. Billardet al (1995) Identification of the primary muscarinic autoreceptor subtype in rat striatum as M2 through a correlation of in vivo microdialysis and in vitro receptor binding data. J.Pharmacol.Exp.Ther. 273 273. PMID: 7714776. Hammeret al (1986) Binding profile of a novel cardioselective muscarinic receptor antagonist, AF-DX 116, to membranes of peripheral tissues and brain in the rat. Life Sci. 38 1653. PMID: 3754610. |