| 货号 | 0678/50 |
| 别名 | (1S,2R)-cis-5-Methoxy-1-methyl-2-(N |
| 供应商 | Tocris |
| 生物活性 | Dopamine receptor antagonist with preferential action at presynaptic receptors (pKi values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD3. hD4, hD2S, hD2L and rD2 receptors respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 269.81 |
| 分子式 | C15H23NO.HCl |
| 可溶性/溶解性 | Soluble to 10 mM in water |
| CAS号 | 85379-09-5 |
| 参考文献 | Millanet al (2004) The role of dopamine D3 compared with dopamine D2 receptors in the control of locomotor activity: a combined behavioural and neurochemical analysis with novel, selective antagonists in rats. Psychopharmacology 174 341. PMID: 14985929. Waterset al (1994) Intracerebral infusion of (+)-AJ76 and (+)-UH232: effects on dopamine release and metabolism in vivo. Eur.J.Pharmacol. 251 181. PMID: 8149975. Kullingsjoet al (1991) Effects of repeated administration of the preferential dopamine autoreceptor antagonist, (+)-AJ76, on locomotor activity and brain DA metabolism in the rat. Eur.J.Pharmacol. 205 241. PMID: 1817961. Johanssonet al (1987) Resolved cisandtrans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. J.Med.Chem. 30 602. PMID: 3560156. |