货号 | 89320-25mg |
描述 | 8-Hydroxy-2-deoxyguanosine is produced by oxidative damage of DNA by reactive oxygen and nitrogen species, including hydroxyl radical and peroxynitrite. It serves as a measure of oxidative stress in biological systems.1,2,3,4 |
别名 | 8-OH-dG; |
供应商 | Cayman |
应用文献 | |
1.Floyd, R.A. Role of oxygen free radicals in carcinogenesis and brain ischemia. The FASEB Journal 4, 2587-2597 (1990). 2.Beckman, K.B. and Ames, B.N. Oxidative decay of DNA. The Journal of Biological Chemisty 272, 19633-19636 (1997). 3.Spencer, J.P.E.,Jenner, A.,Chimel, K., et al. DNA strand breakage and base modification induced by hydrogen peroxide treatment of human respiratory tract epithelial cells. FEBS Letters 374, 233-236 (1995). 4.Epe, B.,Ballmaier, D.,Roussyn, I., et al. DNA damage by peroxynitrite characterized with DNA repair enzymes. Nucleic Acids Research 24, 4105-4110 (1996). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | 22 |
纯度 | ≥98% |
计算分子量 | 283.2 |
分子式 | C10H13N5O5 |
CAS号 | 88847-89-6 |
稳定性 | ≥ 1 year |
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