GSK650394
货号：
17001-50mg 基本售价：
9520.0 元 规格：
50 mg
产品信息
概述| 货号 | 17001-50mg |
| 描述 | GSK650394 is an inhibitor of serum- and glucocorticoid-regulated kinase (IC50s = 62 and 103 nM for SGK1 and SGK2, respectively).1 It demonstrates greater than 30-fold selectivity for SGK1 over Akt and other related kinases.1 GSK650394 can inhibit the androgen-stimulated growth of human prostate carcinoma LNCaP cells with an IC50 value of ~ 1 μM.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Sherk, A.B.,Frigo, D.E.,Schnackenberg, C.G., et al. Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic. Cancer Research 68(18), 7475-7483 (2008).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 382.5 |
| 分子式 | C25H22N2O2 |
| CAS号 | 890842-28-1 |
| 稳定性 | ≥ 2 years |
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