Ro 25-6981 (maleate)
货号：
14578-50mg 基本售价：
9450.0 元 规格：
50 mg
产品信息
概述| 货号 | 14578-50mg |
| 描述 | Ro 25-6981 (maleate) is a potent, selective activity-dependent blocker of NMDA receptors containing the NR2B subunit (IC50s = 9 nM and 52 μM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A, respectively).1 Ro 25-6981 (maleate) displays neuroprotectant effects in vitro, protecting cortical neurons against glutamate toxicity and combined oxygen and glucose deprivation with IC50 values of 0.4 and 0.04 μM, respectively.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Fischer, G.,Mutel, V.,Trube, G., et al. Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro. Journal of Pharmacology and Experimental Therapeutics 283(3), 1285-1292 (1997).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 22 |
| 纯度 | ≥98% |
| 计算分子量 | 455.6 |
| 分子式 | C22H29NO2 • C4H4O4 |
| CAS号 | 1312991-76-6 |
| 稳定性 | ≥ 6 months |
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