13,14-dihydro-15-keto-tetranor Prostaglandin D2
货号：
13100-100ug 基本售价：
9408.0 元 规格：
100 ug
产品信息
概述| 货号 | 13100-100ug |
| 描述 | A common metabolic pathway for several prostaglandins (PGs), including PGD2, involves the reduction of the double bond between C-13 and C-14 and oxidation of the hydroxyl group at C-15, producing 13,14-dihydro-15-keto PGs. The removal of four carbons at the α-terminus and oxidation of the terminal ω-carbon produces the abundant urinary metabolites, including tetranor-PGDM.1 13,14-dihydro-15-keto-tetranor PGD2 is a potential metabolite of PGD2. It would be produced from the known metabolite 13,14-dihydro-15-keto PGD2 (Item No. 12610), which is a known agonist for the CRTH2/DP2receptor.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Song, W.L.,Wang, M.,Ricciotti, E., et al. Tetranor PGDM, an abundant urinary metabolite reflects biosynthesis of prostaglandin D2 in mice and humans. The Journal of Biological Chemisty 283(2), 1179-1188 (2008).
2.Rangachari, P.K., and Betti, P.A. Biological activity of metabolites of PGD2 on canine proximal colon. American Journal of Physiology 264, G886-G894 (1993).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 298.4 |
| 分子式 | C16H26O5 |
| CAS号 | 1204116-69-7 |
| 稳定性 | ≥ 6 months |
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