Lin28 1632 ( )
货号：
6068/50 基本售价：
9359.3 元 规格：
50 mg
产品信息
概述| 货号 | 6068/50 |
| 别名 | N-Methyl-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]acetamide |
性能| 供应商 | Tocris |
| 生物活性 | RNA binding protein Lin28 inhibitor (IC50 = 8 μM). Blocks binding of Lin28 to let-7 pre-micro RNA. Inhibits stemness and induces differentiation of murine ESCs. Inhibits growth of tumor cell lines and tumor-sphere formation in vitro. Also bromodomain inhibitor. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 281.31 |
| 分子式 | C15H15N5O |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Rooset al (2016) A small-molecule inhibitor of Lin28. ACS Chem.Biol. 11 2773. PMID: 27548809. |
