Ceefourin 1 ( )
货号：
5867/50 基本售价：
9359.3 元 规格：
50 mg
产品信息
概述| 货号 | 5867/50 |
| 别名 | 5-[(2-Benzothiazolylthio)methyl]-2,4-dihydro-4-methyl-3H-1,2,4-triazole-3-thione |
性能| 供应商 | Tocris |
| 生物活性 | Selective MRP (multidrug resistance-associated protein) 4 inhibitor (IC50 = 2.6 μM). Selective for MRP4 over P-gp, MRP1 and ABCG2. Sensitizes MRP4 over-expressing cells to SN 38 (Cat. No. 2684). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 294.42 |
| 分子式 | C11H10N4S3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Cheunget al (2014) High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4). Biochem.Pharmacol. 91 97. PMID: 24973542. |
