ZK 756326 (50 MG)
货号：
2565/50 基本售价：
9359.3 元 规格：
50 mg
产品信息
概述| 货号 | 2565/50 |
| 别名 | 2-[2-[4-[(3-phenoxyphenyl)methyl]-1-piperazinyl]ethoxy]ethanol dihydrochloride |
性能| 供应商 | Tocris |
| 生物活性 | Selective, non-peptide CCR8 chemokine receptor agonist (IC50 values are 1.8 and 2.6 μM for human and mouse receptors respectively). Displays no activity at CCR4, CXCR3, CXCR4 and CCR5 and shows > 28-fold selectivity over 26 other GPCRs (less selective at α2A and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 429.38 |
| 分子式 | C21H28N2O3.2HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 874911-96-3 |
| 参考文献 | Haskellet al (2006) Identification and characterization of a potent, selective nonpeptide agonist of the CC chemokine receptor CCR8. Mol.Pharmacol. 69 309. PMID: 16221874. |
