| 货号 | 3366/50 |
| 别名 | 7-Bromo-2-(4-hydroxyphenyl)-1,3-ben |
| 供应商 | Tocris |
| 生物活性 | Selective ERβ receptor agonist that displays 68-fold selectivity over ERα(EC50 values are 2 and 155 nM for ERβ and ERα respectively). Displays antianxiolytic and antidepressive effects in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 306.11 |
| 分子式 | C13H8BrNO3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| CAS号 | 440122-66-7 |
| 参考文献 | Clippertonet al (2008) Differential effects of estrogen receptor alpha and beta specific agonists on social learning of food preferences in female mice. Neuropsychopharmacology 33 2362. PMID: 18004284. Hugheset al (2008) WAY-200070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agent. Neuropharmacology 54 1136. PMID: 18423777. Malamaset al (2004) Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-β ligands. J.Med.Chem. 47 5021. PMID: 15456246. |