VU 0238429 (50 MG)
货号：
3634/50 基本售价：
9359.3 元 规格：
50 mg
产品信息
概述| 货号 | 3634/50 |
| 别名 | 1-(4-Methoxybenzyl)-5-trifluoromethoxyisatin |
性能| 供应商 | Tocris |
| 生物活性 | Selective positive allosteric modulator of M5 receptors (EC50 values are 1.16, >30 and >30 μM at M5, M1 and M3 receptors respectively). Displays no activity at M2 and M4receptors. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 351.28 |
| 分子式 | C17H12F3NO4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Bridgeset al (2009) Discovery of the first highly M5-preferring muscarinic acetylcholine receptor ligand, an M5 positive allosteric modulator derived from a series of 5-trifluoromethoxy N-benzyl isatins. J.Med.Chem. 52 3445. PMID: 19438238. |
