货号 | 1257/50 |
别名 | 22-Oxovincaleukoblastine |
供应商 | Tocris |
生物活性 | Anticancer agent; microtubule disrupter. Induces apoptosis in human lymphoma cells. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >96 % |
计算分子量 | 923.04 |
分子式 | C46H56N4O10.H2SO4 |
可溶性/溶解性 | Soluble to 100 mM in water |
CAS号 | 2068-78-2 |
参考文献 | Wanget al (1999) The effect of antimicrotubule agents on signal transduction pathways of apoptosis. Cancer Chemother.Pharmacol. 44 355. PMID: 10501907. Takanoet al (1993) Apoptosis induced by microtubule disrupting drugs in cultured human lymphoma cells. Inhibitory effects of phorbol ester and zinc sulphate. Pathol.Res.Pract. 189 197. PMID: 8321748. Jordanet al (1985) Comparison of the effects of vinblastine, vincristine, vindesine, and vinepidine on microtubule dynamics and cell proliferation in vitro. Cancer Res. 45 2741. PMID: 3986806. |