| 货号 | 1972/50 |
| 别名 | 7-[(3-Chloro-6,11-dihydro-6-methyl- |
| 供应商 | Tocris |
| 生物活性 | Selective facilitator of 5-HT uptake in vitroandin vivo. Has no affinity for a wide range of receptors, including 5-HT and dopamine (IC50 > 10 μM) and has no effect on noradrenalin or dopamine uptake. Antidepressant, analgesic and neuroprotective following systemic administration in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 458.93 |
| 分子式 | C21H24ClN2NaO4S |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 10 mM in DMSO |
| CAS号 | 30123-17-2 |
| 参考文献 | Plaisantet al (2003) Neuroprotective properties of tianeptine: interactions with cytokines. Neuropharmacology 44 801. PMID: 12681378. Uzbayet al (1999) Analgesic effect of tianeptine in mice. Life Sci. 64 1313. PMID: 10227587. Kato and Weitsch (1988) Neurochemical profile of tianeptine, a new antidepressant drug. Clin.Neuropharmacol. 11 S43. PMID: 3052825. Menniniet al (1987) Tianeptine, a selective enhancer of serotonin uptake in rat brain. Naunyn-Schmied.Arch.Pharmacol. 336478. |