TC-P 262 (50 MG)
货号:
4386/50 基本售价:
9359.3 元 规格:
50 mg
产品信息
概述货号 | 4386/50 |
别名 | 5-[5-Methyl-2-(1-methylethyl)phenoxy]-2,4-pyrimidinediamine |
性能供应商 | Tocris |
生物活性 | Selective P2X3 and P2X2/3 receptor antagonist (pIC50 values are 7.39 and 6.68 respectively). Displays no detectable activity at P2X1, P2X2, P2X4 and P2X7 receptors (pIC50 < 4.7). |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 258.32 |
分子式 | C14H18N4O |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
参考文献 | Balliniet al (2011) Characterization of three diaminopyrimidines as potent and selective antagonists of P2X3 and P2X2/3 receptors with in vivo efficacy in a pain model. Br.J.Pharmacol. 163 1315. PMID: 21410458. |