| 货号 | 1284/25 |
| 别名 | 6-(Benzylamino)-2-(2-hydroxyethylam |
| 供应商 | Tocris |
| 生物活性 | Cyclin-dependent kinase inhibitor that competes for the ATP binding site of the kinase. Selectively inhibits cdc2/cyclin B (IC50 = 7 μM), cdk2/cyclin A (IC50 = 7 μM), cdk2/cyclin E (IC50 = 7 μM), cdk/p35 kinase (IC50 = 3 μM) |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 298.35 |
| 分子式 | C15H18N6O |
| 可溶性/溶解性 | Soluble to 50 mM in ethanol |
| CAS号 | 101622-51-9 |
| 参考文献 | Alessiet al (1998) The cyclin-dependent kinase inhibitors olomoucine and roscovitine arrest human fibroblasts in G1 phase by specific inhibition of CDK2 kinase activity. Exp.Cell.Res. 245 8. PMID: 9828096. Abrahamet al (1995) Cellular effects of olomoucine, an inhibitor of cyclin-dependent kinases. Biol.Cell 83 105. PMID: 7549905. Veselyet al (1994) Inhibition of cyclin-dependent kinases by purine analogues. Eur.J.Biochem. 224 771. PMID: 7925396. |