货号 | 2096/50 |
别名 | 8-Methyl-8-azabicyclo-3-endo[3.2.1] |
供应商 | Tocris |
生物活性 | Selective muscarinic M3 receptor antagonist. In bovine tracheal smooth muscle, inhibits methacholine-dependent effects on cell proliferation and muscle contractility. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 351.83 |
分子式 | C17H21N3O3.HCl |
可溶性/溶解性 | Soluble to 50 mM in water and to 100 mM in DMSO |
CAS号 | 131780-47-7 |
参考文献 | Gosenset al (2004) Muscarinic M3 receptor-dependent regulation of airway smooth muscle contractile phenotype. Br.J.Pharmacol. 141 943. PMID: 14993104. Gosenset al (2003) Muscarinic M3-receptors mediate cholinergic synergism of mitogenesis in airway smooth muscle. Am.J.Respir.Cell Mol.Biol. 28 257. PMID: 12540494. Doodset al (1993) Characterization of muscarinic receptors in guinea-pig uterus. Eur.J.Pharmacol. 250 223. PMID: 8112383. Roffelet al (1993) Cholinergic contraction of the guinea pig lung strip is mediated by muscarinic M2-like receptors. Eur.J.Pharmacol. 250 267. PMID: 8112384. |