| 货号 | 4832/50 |
| 别名 | 2-[[(4-Bromophenyl)methyl]thio]-N-[ |
| 供应商 | Tocris |
| 生物活性 | Positive allosteric modulator at mGlu8 receptors. Exhibits anxiolytic effects in mouse models of anxiety. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 392.35 |
| 分子式 | C19H22BrNOS |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Chruscickaet al (2013) Expression of metabotropic glutamate receptors in mammalian cells as a method for identification of new chemical compounds with drug-like activity. Pharmacol.Rep. 6538. Duvoisinet al (2011) Opposing roles of mGluR8 in measures of anxiety involving non-social and social challenges. Behav.Brain Res. 221 50. PMID: 21382421. Duvoisinet al (2010) Acute pharmacological modulation of mGluR8 reduces measures of anxiety. Behav.Brain Res. 212 168. PMID: 20385173. |