ABP 688 (50 MG)
货号：
5229/50 基本售价：
9359.3 元 规格：
50 mg
产品信息
概述| 货号 | 5229/50 |
| 别名 | 3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-oneO-methyloxime |
性能| 供应商 | Tocris |
| 生物活性 | High affinity human mGlu5 receptor antagonist (Ki = 1.7 nM). Inhibits glutamate-induced calcium release from L(tk-) cells expressing human mGlu5 receptors (IC50 = 2.3 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 240.3 |
| 分子式 | C15H16N2O |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in 1eq. HCl |
| 参考文献 | Hintermannet al (2007) ABP688, a novel selective and high affinity ligand for the labeling of mGlu5 receptors: identification, in vitro pharmacology, pharmacokinetic and biodistribution studies. Bioorg.Med.Chem. 15 903. PMID: 17110115. |
