| 货号 | 2490/50 |
| 别名 | Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]p |
| 供应商 | Tocris |
| 生物活性 | Selective, high affinity P2Y12 receptor antagonist (pKi = 6.9 for hP2Y12 receptor). Inhibits ADP-induced platelet aggregation; potent antithrombotic agent. Requires bioactivation, unlike PSB 0739 (Cat. No. 3983). (+)-Clopidogrel hydrogen sulfate (Cat. No. 1820) also available. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 358.28 |
| 分子式 | C16H16NO2SCl.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 90055-48-4 |
| 参考文献 | Kugelgen (2006) Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol.Ther. 110 415. PMID: 16257449. Savi and Herbert (2005) Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin.Thromb.Haemostas. 31174. Saviet al (2001) P2Y12, a new platelet ADP receptor, target of clopidogrel. Biochem.Biophys.Res.Comm. 283379. |