| 货号 | 0496/50 |
| 别名 | trans-(-)-3,4-Dichloro-N-methyl-N-[ |
| 供应商 | Tocris |
| 生物活性 | More active enantiomer of (±)-U-50488 (Cat. No. 0495). (+)-U-50488 hydrochloride (Cat. No. 0471) also available. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 405.79 |
| 分子式 | C19H26Cl2N2O.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| CAS号 | 67198-19-0 |
| 参考文献 | Zhuet al (1998) Agonist-induced desensitization and down-regulation of the human kappa opioid receptor expressed in chinese hamster ovary cells. J.Pharmacol.Exp.Ther. 285 28. PMID: 9535991. Morroneet al (1993) Withdrawal contractures of guinea-pig isolated ileum after acute activation of κ opioid receptors. Br.J.Pharmacol. 109 48. PMID: 8388301. Reddy and Bhargava (1993) Effect of chronic administration of U-50,488H, a kappa opioid receptor agonist on central dopamine (D2) receptors of the rat. Eur.J.Pharmacol. 235 23. PMID: 8390939. De Costaet al (1987) Synthesis and absolute configuration of optically pure enantiomers of a κ-opioid receptor selective antagonist. FEBS Lett. 223 335. PMID: 2822490. |