SGC-CBP30
货号：
14469-50mg 基本售价：
9352.0 元 规格：
50 mg
产品信息
概述| 货号 | 14469-50mg |
| 描述 | cAMP-responsive element-binding protein binding protein (CREBBP) and E1A-associated protein p300 (EP300) are transcriptional co-activators. Each contains a bromodomain, which recognizes acetylated lysine residues on target proteins. SGC-CBP30 is a potent inhibitor of CREBBP and EP300 bromodomains (IC50s = 21-69 and 38 nM, respectively).1 Developed by the Structural Genomics Consortium (SGC), this compound displays over 40-fold selectivity for CREBBP over BRD4(1) and is functional in cells. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Gallenkamp, D.,Gelato, K.A.,Haendler, B., et al. Bromodomains and their pharmacological inhibitors. ChemMedChem 9(3), 438-464 (2014).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 509 |
| 分子式 | C28H33ClN4O3 |
| CAS号 | 1613695-14-9 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
