Asterric Acid
货号：
70630-5mg 基本售价：
9184.0 元 规格：
5 mg
产品信息
概述| 货号 | 70630-5mg |
| 描述 | Asterric acid is an antibiotic fungal metabolite that completely inhibits the binding of the potent vasoconstrictor endothelin (ET)-1 to the ETA receptor in A10 cells at 0.1 μM.1 Asterric acid derivatives have also been shown to inhibit VEGF-induced tube formation of human umbilical vein endothelial cells at 3-10 μM, which suggests its usefulness as an antiangiogenic agent.2 |
| 别名 | Dimethylosoic Acid;RES-1214-1;TAN 1415A; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Ohashi, H.,Akiyama, H.,Nishikori, K., et al. Asterric acid, a new endothelin binding inhibitor. Journal of Antibiotics 45, 1684-1685 (1992).
2.Lee, H.J.,Lee, J.H.,Hwang, B.Y., et al. Fungal metabolites, asterric acid derivatives inhibit vascular endothelial growth factor (VEGF)-induced tube formation of HUVECs. J.Antibiot.(Tokyo) 55(6), 552-556 (2002).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% |
| 计算分子量 | 348.3 |
| 分子式 | C17H16O8 |
| CAS号 | 577-64-0 |
| 稳定性 | ≥ 2 years |
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