CG 4305
货号:
10012447-1mg 基本售价:
9184.0 元 规格:
1 mg
产品信息
概述货号 | 10012447-1mg |
描述 | Prostacyclin (PGI2) is a cyclooxygenase metabolite with antithrombotic properties found in vascular endothelial cells. The half-life is short both in vivoandin vitro, ranging from 30 seconds to a few minutes. CG 4305 is a stable carbacyclic analog of PGI2 that inhibits ADP-induced platelet aggregation 25% at a concentration of 50 nM.1 Doses of 10 mg/kg (oral) or 1 mg/kg (intraduodenal) have been shown to prevent rabbit carotid artery thrombosis. |
性能供应商 | Cayman |
应用文献 |
1.Maurin, N. Influence on platelet activity and red cell fluidity of epoprostenol and two stable prostacyclin analogues in vitro. Arzneimittel-Forschung/Drug Research 36(8), 1180-1183 (1986).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 396.5 |
分子式 | C25H32O4 |
稳定性 | ≥ 1 year |
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