Rivaroxaban
货号：
16043-50mg 基本售价：
9100.0 元 规格：
50 mg
产品信息
概述| 货号 | 16043-50mg |
| 描述 | Rivaroxaban is an orally active, direct inhibitor of Factor Xa (Ki = 0.4 nM), which is a crucial component of the intrinsic and extrinsic pathways of the blood coagulation cascade.1 It demonstrates >10,000-fold greater selectivity for Factor Xa compared to other related serine proteases.1 In various animal arterial and venous thrombosis models, rivaroxaban is reported to inhibit thrombin formation without prolonging bleeding time and has been approved for clinical use as an anticoagulant in the prevention of stroke and the treatment of venous thromboembolisms.2,3 |
| 别名 | BAY 59-7939;Xarelto®; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Turpie, A.G.G. Oral, direct factor Xa inhibitors in development for the prevention and treatment of thromboembolic diseases. Arterioscler. Thromb. Vasc. Biol. 27(6), 1238-1247 (2007).
2.Babilonia, K. and Trujillo, T. The role of prothrombin complex concentrates in reversal of target specific anticoagulants. Thromb. J. 12:8, (2014).
3.Turpie, A.G.G. Rivaroxaban as an oral anticoagulant for stroke prevention in atrial fibrillation. Ther. Clin. Risk Manag. 10, 197-205 (2014).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 435.9 |
| 分子式 | C19H18ClN3O5S |
| CAS号 | 366789-02-8 |
| 稳定性 | ≥ 2 years |
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