| 货号 | 22063-2.5mg |
| 描述 | Spirolaxine is a long-chain phthalide produced by the fungus S. laxum that has antibacterial properties.1,2 Spirolaxine is a potent anti-H. pylori agent (MIC = 0.2 µg/cm3) with weak activity against E. coli.2,3 Spirolaxine (1-40 µM) inhibits proliferation of endothelial (BMEC, HUVEC) and tumor (LoVo, HL60) cells in culture.4B. megateriumandC. echinulate produce hydroxylated metabolites of spirolaxine when given spirolaxine as a substrate.5 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Arnone, A.,Assante, G.,Nasini, G., et al. Spirolaxine and sporotricale: Two long-chain phthalides produced by Sporotrichum laxum. Phytochemistry 29(2), 613-616 (1990). 2.Guadliana, M.A.,Huang, L.H. and Kaneko, T. Process for preparing spirolaxine and spirolaxine methyl ether. (2000). 3.León, A.,Del-Ángel, M.,Ávila, J.L., et al. Phthalides: Distribution in nature, chemical reactivity, synthesis, and biological activity. Prog. Chem. Org. Nat. Prod. 104, 127-246 (2017). 4.Giannini, G.,Pisano, C.,Riccioni, T., et al. Spirolaxine, a fungal metabolite from Sporotrichum laxum: Determination of relative stereochemistry and biological activity in vitro. Proc. Amer. Assoc. Cancer Res. 64(7 suppl), (2004). 5.Nasini, G.,Bava, A.,Fronza, G., et al. Microbial transformation of spirolaxine, a bioactive undecaketide fungal metabolite from the basidiomycete Sporotrichum laxum. Chem. Biodivers. 4(12), 2772-2779 (2007). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 404.5 |
| 分子式 | C23H32O6 |
| CAS号 | 126382-01-2 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |