SE 175
货号：
82340-100mg 基本售价：
9016.0 元 规格：
100 mg
产品信息
概述| 货号 | 82340-100mg |
| 描述 | SE 175 is an organic nitrate compound of the same general class as nitroglycerin. These nitrate compounds can act as NO-donors in vivo following reductive transformation of the nitrate group to nitric oxide. The nitroxyacylated thiosalicylates, such as SE 175, were developed in an effort to facilitate this reductive process and accelerate the release of NO. SE 175 is stable in buffer or saline solution. In the intact rat, it stimulates endothelial soluble guanylate cyclase and induces aortic vasorelaxation with an EC50 of 20 µM, which is intermediate in potency between nitroglycerine and isosorbide dinitrate.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Endres, S.,Hacker, A.,Noack, E., et al. NO-donors, Part 3: Nitrooxyacylated thiosalicylates and salicylates-synthesis and biological activities. European Journal of Medicinal Chemistry 34, 895-901 (1999).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥97% |
| 计算分子量 | 347.3 |
| 分子式 | C16H13NO6S |
| CAS号 | 258278-64-7 |
| 稳定性 | ≥ 1 year |
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