IQ-1
货号：
16153-50mg 基本售价：
8932.0 元 规格：
50 mg
产品信息
概述| 货号 | 16153-50mg |
| 描述 | IQ-1 is a cell-permeable tetrahydroisoquinolinylidene compound that maintains long-term mouse embryonic stem cell (ESC) pluripotency.1 When used at 4 µg/ml with Wnt3a, it allows ESCs to form embryoid bodies that continue to express markers of pluripotency, including α-fetoprotein and β-III tubulin.1 IQ-1 blocks the interaction of the protein Naked cuticle with a subunit of the protein phosphatase PP2A, altering signaling through Wnt/β-catenin and maintaining the expression of stem cell markers Oct4, Nanog, and Rex1 in ESCs.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Miyabayashi, T.,Teo, J.L.,Yamamoto, M., et al. Wnt/β-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency. Proceedings of the National Academy of Sciences of the United States of America 104(13), 5668-5673 (2007).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 362.4 |
| 分子式 | C21H22N4O2 |
| CAS号 | 331001-62-8 |
| 稳定性 | ≥ 2 years |
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