15(R)-Prostaglandin F2α
货号：
16740-10mg 基本售价：
8820.0 元 规格：
10 mg
产品信息
概述| 货号 | 16740-10mg |
| 描述 | 15(R)-PGF2α is the C-15 epimer of the naturally occurring mammalian autacoid PGF2α. It has only 25% of the potency of PGF2α in hamster antifertility studies,1 which may be due to reduced affinity for FP receptors. Compared to PGF2α, 15(R)-PGF2α has a binding affinity of 6.7% to ovine luteal cell receptors.2 Similarly, the binding affinity to rat vascular smooth muscle cells is negligible as compared to PGF2α.3 |
| 别名 | 15-epiPGF2α; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Miller, W.L., and Sutton, M.J. Relative biological activity of certain prostaglandins and their enantiomers. Prostaglandins 11, 77-84 (1976).
2.Balapure, A.K.,Rexroad, C.E., Jr.,Kawada, K., et al. Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2α receptor. Biochemical Pharmacology 38, 2375-2381 (1989).
3.Hanasaki, K.,Kishi, M., and Arita, H. Phorbol ester-induced expression of the common, low-affinity binding site for primary prostanoids in vascular smooth muscle cells. The Journal of Biological Chemisty 265, 4871-4875 (1990).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 354.5 |
| 分子式 | C20H34O5 |
| CAS号 | 37658-84-7 |
| 稳定性 | ≥ 1 year |
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