货号 | 16208-100mg |
描述 | Dimetridazole is a nitroimidazole-based compound with antibacterial and anticoccidial activity.1 It was once widely used in the treatment of parasitic infections in poultry, cattle, swine and farmed fish until suspected to be carcinogenic and mutagenic to humans.2 Hydroxy dimetridazole is a metabolite of dimetridazole that may be useful for identifying this nitroimidazole in various agricultural samples through liquid chromatography–tandem mass spectrometry and other methods.2,3,4 |
别名 | HMMNI;2-Hydroxymethyl-1-methyl-5-Nitroimidazole; |
供应商 | Cayman |
应用文献 | |
1.Jokipii, L. and Jokipii, A.M.M. Comparative evaluation of the 2-methyl-5-nitroimidazole compounds dimetridazole, metronidazole, secnidazole, ornidazole, tinidazole, carnidazole, and panidazole against Bacteroides fragilis and other bacteria of the Bacteroides fragilis group. Antimicrobial Agents and Chemotherapy 28(4), 561-564 (1985). 2.Sakamoto, M.,Takeba, K.,Sasamoto, T., et al. Determination of dimetridazole, metronidazole and ronidazole in salmon and honey by liquid chromatography coupled with tandem mass spectrometry. J.Food Hyg.Soc.Jpn. 52(1), 51-58 (2011). 3.Tölgyesi, A.,Sharma, V.K.,Fekete, S., et al. Development of a rapid method for the determination and confirmation of nitroimidazoles in six matrices by fast liquid chromatography-tandem mass spectrometry. Journal of Pharmaceutical & Biomedical Analysis 64-65, 40-48 (2012). 4.Mohamed, R.,Mottier, P.,Treguier, L., et al. Use of molecularly imprinted solid-phase extraction sorbent for the determination of four 5-nitroimidazoles and three of their metabolites from egg-based samples before tandem LC-ESIMS/MS analysis. Journal of Agricultural and Food Chemistry 56(10), 3500-3508 (2008). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 157.1 |
分子式 | C5H7N3O3 |
CAS号 | 936-05-0 |
稳定性 | ≥ 2 years |
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