IDFP
货号：
10215-10mg 基本售价：
8820.0 元 规格：
10 mg
产品信息
概述| 货号 | 10215-10mg |
| 描述 | The endocannabinoids, 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (AEA), are biologically active lipids that regulate diverse neurological and metabolic functions by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2). Monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH) hydrolyze 2-AG and AEA, respectively, thus terminating their biological function. IDFP is an organophosphorus compound that dually inhibits MAGL and FAAH with IC50 values of 0.8 and 3 nM, respectively.1 At 10 mg/kg, IDFP elevates brain levels of 2-AG and AEA more than 10-fold, and decreases levels of arachidonic acid by a similar magnitude.1 |
| 别名 | Isopropyl Dodecylfluorophosphonate; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Nomura, D.K.,Blankman, J.L.,Simon, G.M., et al. Activation of the endocannabinoid system by organophosphorus nerve agents. Nature Chemical Biology 4(6), 373-378 (2008).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 294.4 |
| 分子式 | C15H32FO2P |
| CAS号 | 615250-02-7 |
| 稳定性 | ≥ 1 year |
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