Polymyxin B1
货号:
14074-10mg 基本售价:
8750.0 元 规格:
10 mg
产品信息
概述货号 | 14074-10mg |
描述 | The polymyxins are cationic peptides originally isolated from B. polymyxa.1 They bind and kill Gram-negative bacteria.2 The B series of polymyxins consist of a cyclic heptapeptide and a tripeptide side chain acylated at the amino terminus by a fatty acid. Polymyxin B1 is a form of polymyxin B which terminates with 6-methyloctanamide. Polymyxin B1 is comparable to other B polymyxins in its ability to kill P. aeruginosa,A. baumannii, and K. pneumoniaeisolates.3 Its relative pharmacokinetics and nephrotoxicity have not been examined. |
性能供应商 | Cayman |
应用文献 |
1.Falagas, M.E. and Kasiakou, S.K. Toxicity of polymyxins: A systematic review of the evidence from old and recent studies. Critical Care 10(1), (2006). 2.Hancock, R.E.W. Cationic peptides: Effectors in innate immunity and novel antimicrobials. Lancet Infect.Dis. 1(3), 156-164 (2001). 3.Tam, V.H.,Cao, H.,Ledesma, K.R., et al. In vitro potency of various polymyxin B components. Antimicrobial Agents and Chemotherapy 55(9), 4490-4491 (2011).
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运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 1203.5 |
分子式 | C56H98N16O13 |
CAS号 | 816631 |
稳定性 | ≥ 1 year |
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