WDR5 0103 (50 MG)
货号：
5323/50 基本售价：
8704.9 元 规格：
50 mg
产品信息
概述| 货号 | 5323/50 |
| 别名 | 3-[(3-Methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)benzoic acid methyl ester |
性能| 供应商 | Tocris |
| 生物活性 | WD repeat-containing protein 5 (WDR5) antagonist (Kd = 450 nM). Disrupts WDR5 interaction with MLL and inhibits MLL core complex methyltransferase activity in vitro. Has no effect on a panel of seven other methyltransferases, including SETD7. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 383.44 |
| 分子式 | C21H25N3O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| 参考文献 | Senisterraet al (2013) Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5. Biochem.J. 449 151. PMID: 22989411. |
