| 货号 | 0751/50 |
| 别名 | (±)-Tropanyl 2-(4-chlorophenoxy)butanoate maleate |
| 供应商 | Tocris |
| 生物活性 | Potent and selective σ2 antagonist with central effects following systemic administration. Causes increased release of acetylcholine at central muscarinic synapses. Potent analgesic (efficacy comparable to morphine) and nootropic agent. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 453.92 |
| 分子式 | C18H24ClNO3.C4H4O4 |
| 可溶性/溶解性 | Soluble to 25 mM in water |
| CAS号 | 155058-71-2 |
| 参考文献 | Matsumoto and Mack (2001) (±)-SM 21 attenuates the convulsive and locomotor stimulatory effects of cocaine in mice. Eur.J.Pharmacol. 417 R1. PMID: 11301071. Ghelardiniet al (2000) Pharmacological identification of SM-21, the novel σ2 antagonist. Pharmacol.Biochem.Behav. 67 659. PMID: 11164098. Ghelardiniet al (1997) Antinociceptive profile of 3-α-tropanyl-(2-Cl)-acid phenoxybutyrate (SM-21): a novel analgesic with a presynaptic cholinergic mechanism of action. J.Pharmacol.Exp.Ther. 282 430. PMID: 9223584. |