| 货号 | 3313/50 |
| 别名 | 5,7-Bis(1,1-dimethylethyl)-3-hydrox |
| 供应商 | Tocris |
| 生物活性 | Potent and selective GABAB receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectively). Exhibits anxiolytic activity in vivo and is orally active. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 330.34 |
| 分子式 | C17H21F3O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 123557-91-5 |
| 参考文献 | Koeket al (2013) Discriminative stimulus effects of the GABAB receptor-positive modulator rac-BHFF: comparison with GABAB receptor agonists and drugs of abuse. J.Pharmacol.Exp.Ther. 344 553. PMID: 23275067. Malherbeet al (2008) Characterization of (R,S)-5,7-di-tert-butyl-3-hydroxy-3-trifluoromethyl-3H-benzofuran-2-one as a positive allosteric modulator of GABAB receptors. Br.J.Pharmacol. 154 797. PMID: 18536733. |