货号 | 0837/50 |
别名 | 4-(Z)-6-(2-o-Chlorophenyl-4-o-hydro |
供应商 | Tocris |
生物活性 | Potent thromboxane A2 receptor (TP receptor) antagonist. Competitively inhibits contractile responses to U 46619 (Cat. No. 1932). |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 402.87 |
分子式 | C22H23ClO5 |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
CAS号 | 117621-64-4 |
参考文献 | Caoet al (2004) Thromboxane A2 (TP) receptor in the non-pregnant porcine myometrium and its role in regulation of spontaneous contractile activity. Eur.J.Pharmacol. 485 317. PMID: 14757156. Arakawaet al (1993) Leukotriene D4 and prostaglandin F2a- induced airflow obstruction and airway plasma exudation in guinea pig: role of thromboxane and its receptor. Br.J.Pharmacol. 110 127. PMID: 8220872. Brewsteret al (1988) The synthesis of a novel thromboxane receptor antagonist 4(Z)-6-(2-o-chlorophenyl-4-o-hydroxyphenyl-1,3-dioxan-cis-5-yl)hexenoic acid ICI 192605. Prostaglandins 36 173. PMID: 2973084. |