货号 | 0646/50 |
别名 | 6-[2-(4-Imidazolyl)ethylamino]-N-(4 |
供应商 | Tocris |
生物活性 | H1 and H2 receptor agonist. 4x104 times more active than histamine in H2-mediated effects in natural suppressor cells. Increases intracellular Ca2+ and IP3 in lymphocytes through a binding site other than H1, H2 or H3. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 614.57 |
分子式 | C19H25F3N4O.2C4H4O4 |
可溶性/溶解性 | Soluble to 100 mM in water |
CAS号 | 195867-54-0 |
参考文献 | Shahidet al (2009) Histamine, histamine receptors and their role in immunomodulation: An updated systematic review. Open Immunol.J. 29. Khanet al (1987) Congener derivatives and conjugates of histamine: synthesis and tissue receptor selectivity of the derivatives. J.Med.Chem. 30 2115. PMID: 2959777. Khanet al (1986) The effects of derivatives of histamine on natural suppressor cells. J.Immunol. 137 308. PMID: 3011908. |