货号 | 1471/50 |
别名 | (R)-1-(1-Phenylethyl)-1H-imidazole- |
供应商 | Tocris |
生物活性 | General anesthetic with GABA modulatory and GABA-mimetic actions; selectively interacts with β2- and β3-subunit containing GABAA receptors. Short acting and potent hypnotic, with low toxicity. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 244.29 |
分子式 | C14H16N2O2 |
可溶性/溶解性 | Soluble to 100 mM in ethanol and to 50 mM in 1eq. HCl |
CAS号 | 33125-97-2 |
参考文献 | Moodyet al (1998) Distinct structural requirements for the direct and indirect actions of the anaesthetic etomidate at GABAA receptors. Toxicol.Lett. 100-101 209. PMID: 10049144. Belelliet al (1997) The interaction of the general anesthetic etomidate with the γ-aminobutyric acid type A receptor is influenced by a single amino acid. Proc.Natl.Acad.Sci.U.S.A. 94 11031. PMID: 9380754. Gieseet al (1983) Etomidate: a new intravenous anesthetic induction agent. Pharmacother. 3 251. PMID: 6359080. |