| 货号 | 4784/50 |
| 别名 | 5-[[4-[2-(5-Methyl-2-phenyl-4-oxazo |
| 供应商 | Tocris |
| 生物活性 | Potent and selective PPARγ agonist (EC50 values are 35.6 and 1053 nM for PPARγ and PPARα cofactor recruitment respectively. Enhances insulin sensitivity in obese, but not lean, rats. Antidiabetic and orally bioavailable. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 464.56 |
| 分子式 | C24H20N2O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Dietzet al (2012) Comparative molecular profiling of the PPARα/γ activator aleglitazar: PPAR selectivity, activity and interaction with cofactors. ChemMedChem 7 1101. PMID: 22489042. Fürnsinnet al (1999) Chronic and acute effects of thiazolidinediones BM13.1258 and BM15.2054 on rat skeletal muscle glucose metabolism. Br. J. Pharmacol. 128 1141. PMID: 10578125. |