货号 | 3116/50 |
别名 | 7-Nitro-5-(trifluoromethyl)-2-benzo |
供应商 | Tocris |
生物活性 | Selective, ATP-competitive polo-like kinase 1 (PLK1) inhibitor (IC50 = 500 nM). |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 307.21 |
分子式 | C9H4F3N3O4S |
可溶性/溶解性 | Soluble to 25 mM in DMSO and to 10 mM in ethanol |
CAS号 | 40533-25-3 |
参考文献 | Tayloret al (2008) Ligand discovery and virtual screening using the program LIDAEUS. Br.J.Pharmacol. 153 S55. PMID: 18037921. McInneset al (2006) Inhibitors of polo-like kinase reveal roles in spindle pole maintenance. Nature Chem.Biol. 2608. |