| 货号 | 1427/50 |
| 别名 | 1-[3-(dimethylamino)propyl]-1-(4-fl |
| 供应商 | Tocris |
| 生物活性 | Highly selective and potent 5-HT uptake inhibitor with no effect on noradrenalin or dopamine uptake (IC50 values are 1.8, 8800 and 41000 nM respectively). Has negligible activity at a wide range of receptors. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 405.31 |
| 分子式 | C20H21FN2O.HBr |
| 可溶性/溶解性 | Soluble to 50 mM in ethanol and to 10 mM in water |
| CAS号 | 59729-33-8 |
| 参考文献 | Mateoet al (2000) Inhibition of 5-hydroxytryptamine reuptake by the antidepressant citalopram in the locus coeruleus modulates the rat brain noradrenergic transmission in vivo. Neuropharmacology 39 2036. PMID: 10963747. Auerbach and Hjorth (1995) Effect of chronic administration of the selective serotonin (5-HT) uptake inhibitor citalopram on extracellular 5-HT and apparent autoreceptor sensitivity in rat forebrain in vivo. Naunyn Schmiedebergs Arch.Pharmacol. 352 597. PMID: 9053730. Hyttel (1982) Citalopram - pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity. Prog.Drug Metabolism. Eds. Bridges, J. W. & Ch 6277. |