| 货号 | 0271/50 |
| 别名 | cis-1-Aminocyclobutane-1,3-dicarbox |
| 供应商 | Tocris |
| 生物活性 | Potent, competitive and selective inhibitor of glutamate uptake. Certain confusion exists over the naming of this compound because of apparent contradictions in the literature. This is the isomer which has the carboxylic acid and the amino groups on the same side of the cyclobutyl ring. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 159.14 |
| 分子式 | C6H9NO4 |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. NaOH |
| CAS号 | 73550-55-7 |
| 参考文献 | Kochet al (1999) Differentiation of substrate and nonsubstrate inhibitors of the high-affinity, sodium-dependent glutamate transporters. Mol.Pharmacol. 56 1095. PMID: 10570036. Fletcheret al (1991) Inhibition of L-glutamic acid uptake into rat cortical synaptosomes by the conformationally restricted analogue of glutamic acid, cis-1-aminocyclobutane-1,3-dicarboxylic acid. Neurosci.Lett. 121 133. PMID: 1673544. Allanet al (1990) Synthesis and activity of a potent NMDA agonist, trans-1-aminocyclobutane-1,3-dicarboxylic acid, and related phosphonic and carboxylic acids. J.Med.Chem. 33 2905. PMID: 2145435. |