CDN 1163 ( )
货号：
5869/50 基本售价：
8704.9 元 规格：
50 mg
产品信息
概述| 货号 | 5869/50 |
| 别名 | 4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide |
性能| 供应商 | Tocris |
| 生物活性 | SERCA2 allosteric activator. Increases Ca2+-ATPase activity and Ca2+ uptake by ER microsomes from obese mice. Rescues HEK cells from ER stress-induced cell death. Reduces fasting glucose levels and adipose tissue weight, and increases energy expenditure in ob/ob mice. Also improves glucose tolerance and reverses hepatic steatosis in ob/obmice. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 320.38 |
| 分子式 | C20H20N2O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Kanget al (2016) Small molecular allosteric activator of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) attenuates diabetes and metabolic disorders. J.Biol.Chem. 291 5185. PMID: 26702054. |
