| 货号 | 0524/50 |
| 别名 | 8-[3-(4-Fluorophenoxy)propyl]-1-phe |
| 供应商 | Tocris |
| 生物活性 | Selective 5-HT antagonist, which binds to 5-HT2 sites as potently as spiperone but has lower affinity for 5-HT2C receptors. Also a high affinity D2 receptor antagonist (Ki = 3 nM). Lacks the disruptive effect of spiperone on animal behavior. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 383.46 |
| 分子式 | C22H26FN3O2 |
| 可溶性/溶解性 | Soluble to 75 mM in DMSO |
| CAS号 | 510-74-7 |
| 参考文献 | Czotyet al (2000) Behavioural effects of AMI-193, a 5-HT2A- and dopamine D2-receptor antagonist, in the squirrel monkey. Pharmacol.Biochem.Behav. 67 257. PMID: 11124389. Ismaielet al (1993) Antagonism of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane stimulus with a newly identified 5HT2 versus 5HT1C selective antagonist. J.Med.Chem. 36 2519. PMID: 8355253. |