| 货号 | 0523/50 |
| 别名 | 4-(4-Fluorobenzoyl)-1-(4-phenylbuty |
| 供应商 | Tocris |
| 生物活性 | A selective 5-HT2A antagonist with almost as high affinity (Ki = 5.3 nM) as ketanserin but with a much lower affinity for 5-HT2C sites (Ki = 620 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 429.49 |
| 分子式 | C22H26FNO.C2H2O4 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
| 参考文献 | Hagberget al (1998) Stimulation of 5-HT2A receptors on astrocytes in primary culture opens voltage-independent Ca2+ channels. Neurochem.Int. 32 153. PMID: 9542727. Herndonet al (1992) Ketanserin analogues - structure affinity relationships of 5HT2 and 5HT1C serotonin receptor binding. J.Med.Chem. 35 4903. PMID: 1479590. |