| 货号 | 4133/50 |
| 别名 | 1-[6-[[(17β)-3-Methoxyestra-1,3,5(10 |
| 供应商 | Tocris |
| 生物活性 | Analog of U 73122 (Cat. No. 1268); can be used as a negative control. Inhibits Panx1 currents in HEK cells. Also inhibits vasopressin- and GTPγS-induced Ca2+ influx in hepatocytes. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 466.66 |
| 分子式 | C29H42N2O3 |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO with gentle warming and to 5 mM in ethanol with gentle warming |
| 参考文献 | Kataokaet al (2009) Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT. J.Neurochem. 108 115. PMID: 19014371. Maet al (2009) Pharmacological characterization of pannexin-1 currents expressed in mammalian cells. J.Pharmacol.Exp.Ther. 328 409. PMID: 19023039. Mutoet al (1997) The putative phospholipase C inhibitor U73122 and its negative control, U73343, elicit unexpected effects on the rabbit parietal cell. J.Pharmacol.Exp.Ther. 282 1379. PMID: 9316850. Berven and Barritt (1995) Evidence obtained using single hepatocytes for inhibition by the phospholipase C inhibitor U73122 of store-operated Ca2+ inflow. Biochem.Pharmacol. 49 1373. PMID: 7763279. |