SF 1670 (50 MG)
货号：
5020/50 基本售价：
8615.7 元 规格：
50 mg
产品信息
概述| 货号 | 5020/50 |
| 别名 | N-(9,10-Dihydro-9,10-dioxo-2-phenanthrenyl)-2,2-dimethylpropanamide |
性能| 供应商 | Tocris |
| 生物活性 | PTEN inhibitor. Increases fMLP-elicited PIP3 signaling, Akt -phosphorylation and production of reactive oxygen species in neutrophils in vitro. Pretreatment of transfused neutrophils enhances chemotaxis to sites of bacterial infection and increases survival in neutropenic mice. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 307.34 |
| 分子式 | C19H17NO3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Li (2011) Pretreatment with phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor SF1670 augments the efficacy of granulocyte transfusion in a clinically relevant mouse model. Blood 117 6702. PMID: 21521784. |
